A Better Way Forward in Opioid Withdrawal Management

Wearable Neurostimulation for Opioid Withdrawal

FDA icon blue
FDA-Cleared
drug free icon blue
Non-Invasive/Drug-Free Option
rapid icon blue
Rapid Activation
efficacy icon blue
Proven Efficacy

Effective Opioid Withdrawal Management for Better Patient Outcomes

Whether transitioning patients to MAT/MOUD or helping them eliminate opioids from daily life, rapidly managing opioid withdrawal is a pivotal first step for patients with Opioid Use Disorder (OUD).

For providers, it’s a critical moment in which to stabilize patients or quickly lose them to discharge against medical advice (AMA). In fact, studies show that approximately 10% of patients leave AMA in the first three days of treatment – many of which due to unmanaged withdrawal.¹

Introducing Sparrow Ascent, the better way forward for withdrawal management.

Spark Biomedical's Sparrow Ascent product image

Sparrow Ascent changes the way opioid withdrawal is managed, offering a non-invasive, FDA-cleared solution that directly targets all withdrawal symptoms without introducing drug interactions or systemic side effects.

See How it Works
play2
The Sparrow Ascent is a transcutaneous nerve field stimulator that is intended to be used in patients experiencing opioid withdrawal in conjunction with standard symptomatic medication and other therapies for opioid symptoms under the supervision of trained clinical personnel.
orange triangle icon
Indication for Use
Woman wearing Sparrow Ascent device in kitchen

What Makes Sparrow Ascent Different?

As the first FDA-cleared, non-invasive, wearable neurostimulation device for opioid withdrawal relief, Sparrow Ascent offers:

drug-free icon of crossed out pill bottle

A Drug-Free/Non-Invasive Option –no systemic side effects, no drug interactions, no needles.

Rapid icon orange

Begins working in as little as 30 minutes; 84% of patients report mild to no symptoms within an hour.

Efficacy icon orange

Proven Efficacy – 100% of participants in clinical trials sustained meaningful relief at day 3 and beyond.

Clinical Advantages to Incorporating Sparrow Ascent

High withdrawal-related AMA rates can disrupt treatment goals and drain resources. Sparrow Ascent empowers centers with:

A Resource to Reduce Early Discharges – Put a tool in your toolkit to lower the withdrawal-related AMA rate in the first three days of care.


Optimize Resource Management – Reduce high acuity patient burden on staff with a safe, fast-acting, flexible approach to withdrawal management.


Enhance Patient Engagement – 90% of patients completing detox with Sparrow Ascent continued to the next treatment step.

Maximize Patient Access – Sparrow Ascent can be used across IP, OP and In-home care settings allowing unique treatment options not yet offered by other centers.

Clinical Results at a Glance

84%

of participants experienced mild or no withdrawal symptoms after 60 minutes of therapy.

100%

of participants sustained a clinically meaningful reduction in withdrawal symptoms by day 3.

9/10

participants who completed detox accepted a referral to continue opioid use disorder treatment.

COWS score reduction chart
***Statistically significant difference at each endpoint compared to baseline (p<0.0001)

PHQ-9 and BCL-5 Results

Clinical trial participants also experienced reduction in Depression and PTSD – helping support the recovery journey.

PHQ-9 = Depression
42.9%

of participants had clinically meaningful reduction in PHQ-9 scores at day 5

PCL-5=PTSD
35.7%

of participants sustained a clinically meaningful reduction in withdrawal symptoms by day 3.

Publications & Clinical Trials

At Spark Biomedical, we drive scientific progress through pioneering research, clinical trials, and bringing innovative solutions to market. Below are our efforts supporting solutions in opioid use disorder. See all of our scientific progress on The Neuroscience page.

Clinical Trials

Evaluating the Specific Role of Endogenous Opioids as the Mechanism Underlying tAN-based Analgesia in Healthy Individuals

Status:

Recruiting
SPROUT Trial Phase II: Neurostimulation to Improve NOWS Outcomes

Status:

Recruiting
SPROUT Trial Phase I: Neurostimulation to Improve NOWS Outcomes

Status:

Completed
in 2020
A Non-Invasive, Non-Sedating Device to Mitigate Motion Sickness and Spatial Disorientation

Status:

Not Yet Recruiting
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.

Publications

Frontiers

Transcutaneous Auricular Neurostimulation (tAN): A Novel Adjuvant Treatment in Neonatal Opioid Withdrawal Syndrome

Bioelectronic Medicine

Delivering transcutaneous auricular neurostimulation (tAN®) to improve symptoms associated with opioid withdrawal: results from a prospective clinical trial

Sparrow Ascent Providers

Success Stories

Podcasts & Video Blogs

circle play icon white

Our Origin Story

circle play icon white

Our Clinical Story

circle play icon white

The Vision for Sparrow

Not ready to purchase?

Complete this form to download the Clinical Trial Whitepaper.