Spark Biomedical

Clinical Trials

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Our clinical trials focus on demonstrating the efficacy of transcutaneous auricular neurostimulation (tAN®). Through these studies, we're exploring how wearable neurostimulation can provide reliable, on-demand support for people dealing with challenging symptoms.

This approach opens new doors for patients who need effective, drug-free management options, particularly those who may not respond well to standard treatments or who seek alternatives to traditional pharmaceuticals.

Clinical Trials

Spark Publications
Transcutaneous Auricular Neurostimulation (tAN): A Novel Adjuvant Treatment in Neonatal Opioid Withdrawal Syndrome

Status:

Transcutaneous Auricular Neurostimulation (tAN): A Novel Adjuvant Treatment in Neonatal Opioid Withdrawal Syndrome

Overview

Frontiers in Human Neuroscience: Brain Imaging and Stimulation, 2021

Neonatal Pilot

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Number of Subjects
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ClinicalTrials.gov ID
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Lead Organization
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Funding Source
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Partners
No items found.
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Journal Publication
No current publications
Ongoing Studies
Auricular Neurostimulation for Mood and Climacteric Symptoms in Perimenopausal Women: A Pilot Study

Status:

Protocol Prep

Auricular Neurostimulation for Mood and Climacteric Symptoms in Perimenopausal Women: A Pilot Study

Overview

The purpose of this study is to evaluate the feasibility and preliminary efficacy for transcutaneous auricular neurostimulation (tAN) to improve mood symptoms and decrease climacteric symptoms in women with perimenopause. Participants will use tAN daily for month and complete regular questionnaires weekly. Participants will continue to complete questionnaires for another month without tAN.

Download Whitepaper
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Number of Subjects
Protocol Prep
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ClinicalTrials.gov ID
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Lead Organization
TCU
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Funding Source
TCU
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Partners
No items found.
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Journal Publication
No current publications
Ongoing Studies
Auricular Neurostimulation for Premenstrual Mood Symptoms in PMS/PMDD: A Pilot Study

Status:

Protocol Prep

Auricular Neurostimulation for Premenstrual Mood Symptoms in PMS/PMDD: A Pilot Study

Overview

The purpose of this study is to evaluate the feasibility and preliminary efficacy for transcutaneous auricular neurostimulation (tAN) reduce the symptoms of PMS/PMDD.

Download Whitepaper
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Number of Subjects
Protocol Prep
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ClinicalTrials.gov ID
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Lead Organization
TCU
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Funding Source
TCU
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Partners
No items found.
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Journal Publication
No current publications
Ongoing Studies
Delivering Non-Invasive Transcutaneous Auricular Neurostimulation for Non-surgical Management of Chronic Subdural Hematomas

Status:

Protocol Prep

Delivering Non-Invasive Transcutaneous Auricular Neurostimulation for Non-surgical Management of Chronic Subdural Hematomas

Overview

The purpose of this study is to evaluate the feasibility, safety, and preliminary efficacy of transcutaneous auricular neurostimulation (tAN) as a non-invasive therapy for patients with chronic subdural hematomas (cSDH) managed without surgery

Download Whitepaper
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Number of Subjects
Protocol Prep
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ClinicalTrials.gov ID
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Lead Organization
UT Southwestern
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Funding Source
TRC4
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Partners
No items found.
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Journal Publication
No current publications
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Suite D9 531
Dallas, Texas 75252
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